![]() Each blister on the double-foil strip within the device contains 100, 250, or 500 µg of microfine fluticasone propionate and 72.5 µg of microfine salmeterol xinafoate salt, equivalent to 50 µg of salmeterol base, in 12.5 mg of formulation containing lactose. It is freely soluble in methanol slightly soluble in ethanol, chloroform, and isopropanol and sparingly soluble in water.Īdvair Diskus 100/50, Advair Diskus 250/50, and Advair Diskus 500/50 are specially designed plastic devices containing a double-foil blister strip of a powder formulation of fluticasone propionate and salmeterol xinafoate intended for oral inhalation only. Salmeterol xinafoate is a white to off-white powder with a molecular weight of 603.8, and the empirical formula is C 25H 37NO 4♼ 11H 8O 3. The chemical name of salmeterol xinafoate is 4-hydroxy-a 1-amino]methyl]-1,3-benzenedimethanol, 1-hydroxy-2-naphthalenecarboxylate. Salmeterol xinafoate is the racemic form of the 1-hydroxy-2-naphthoic acid salt of salmeterol. The other active component of Advair Diskus is salmeterol xinafoate, a highly selective beta 2-adrenergic bronchodilator. It is practically insoluble in water, freely soluble in dimethyl sulfoxide and dimethylformamide, and slightly soluble in methanol and 95% ethanol. One active component of Advair Diskus is fluticasone propionate, a corticosteroid having the chemical name S(fluoromethyl) 6a,9-difluoro-11ß,17-dihydroxy-16a-methyl-3-oxoandrosta-1,4-diene-17ß-carbothioate, 17-propionate.įluticasone propionate is a white to off-white powder with a molecular weight of 500.6, and the empirical formula is C 25H 31F 3O 5S. in italics)ĬOST OF THERAPY : $ 111.53 (Asthma Advair Diskus 100 µg 50 µg 2 inhalations/day 30 days)Īdvair Diskus 100/50, Advair Diskus 250/50, and Advair Diskus 500/50 are combinations of fluticasone propionate and salmeterol xinafoate. ![]() 3-D Sinus Imaging – CT Scan of the SinusesĭRUG CLASS : : Adrenergic agonists Bronchodilators Corticosteroids, inhalationīRAND NAMES : Advair Diskus ( US) Seretide (Korea, Philippines, Thailand, South-Africa) Seretide Accuhaler (Australia, Mexico).Why Choose NY Allergy & Sinus Centers The NY Allergy Advantage – At New York Allergy & Sinus Centers, we use leading edge technologies to diagnose your allergies immediately, because we know that faster diagnosis means faster relief.The NY Allergy & Sinus Centers Management Team.
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